IndraLab

Statements


OTUB1 increases the amount of MYC. 3 / 3
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"Consequently, OTUB1 increases c-MYC protein levels and the expression of c-MYC target genes including hexokinase-2, which increase glycolysis and tumor growth."

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"Consequently, OTUB1 increases c-MYC protein levels, which increase glycolysis and tumor growth, and this is related in breast cancer cells (MCF-7 and MDA-MB 231) (48)."

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"OTUB1 directly regulates MYC protein level by catalysing deubiquitination and stabilization [ 46 ]."