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KCNQ1 activates GIP. 2 / 2

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"XREF_BIBR For example, mutations in voltage gated potassium channels KCNQ1 and KCNH1, identified as pathogenic in some individuals with long QT syndrome, may also increase secretion of GLP-1, GIP, and insulin, and impair glucagon secretion."

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"Wolfram syndrome 1 gene (WFS1) has been associated with type 2 diabetes and with impaired insulin secretion during a GLP-1 infusion, and the variant rs151290 in KCNQ1 has been associated with changes in insulin secretion and increased GIP and GLP-1 secretion."

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KCNQ1 activates GIP. 2 / 2

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