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NAMPT phosphorylates INSR. 7 / 7
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"In the same study, the authors demonstrated that visfatin phosphorylated the insulin receptor, insulin receptor substrate-1 (IRS-1) and -2 (IRS-2), PI3K, Akt and MAPK [ xref ]."
18400051
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"In contrast others found that Nampt did not induce insulin receptor phosphorylation or downstream AKT activity when tested on several preadipocyte cell lines xref ."
23536823
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"Furthermore, visfatin induced tyrosine phosphorylation of the insulin receptor, activated downstream insulin signaling pathways such as Erk-1, Akt, and p38 MAPK, and markedly increased the levels of TGFbeta1, PAI-1, type I collagen, and MCP-1 in both renal cells."
20375985
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"We found that visfatin induced tyrosine phosphorylation of IR, IRS-1, and IRS-2."
17340225
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"In the same study, the authors demonstrated that visfatin phosphorylated the insulin receptor, insulin receptor substrate-1 (IRS-1) and -2 (IRS-2), PI3K, Akt and MAPK [XREF_BIBR]."
18400051
reach
"In contrast others found that Nampt did not induce insulin receptor phosphorylation or downstream AKT activity when tested on several preadipocyte cell lines XREF_BIBR."
23536823
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"Although insulin (10 nM) induced significant phosphorylation of the insulin receptor and the downstream signaling kinase Akt in each of these cell lines, equimolar concentrations of eNampt and visfati[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
17983582