IndraLab

Statements

IL6 activates USP17L2. 6 / 6
| 6
reach
"Interestingly, Dub3 activity and expression, at both the mRNA and protein levels, can be induced by IL-6 through the JAK and STAT3 signaling pathway [XREF_BIBR, XREF_BIBR, XREF_BIBR]."
29147673
reach
"In addition, the DUB-3 protein, induced by IL-4 and IL-6, is also involved in the regulation of cell growth and survival where its constitutive expression leads to growth suppression and apoptosis [25[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23773437
reach
"Specifically, Dub3 is rapidly induced by IL-4 and IL-6."
28198361
reach
"Mechanistically, IL-6 induces the deubiquitinase (DUB3), which removes ubiquitin from SNAIL to prevent its proteasomal degradation."
31036052
reach
"In addition, Dub3 can be rapidly induced by inflammatory cytokine IL-6 [XREF_BIBR, XREF_BIBR]."
29088851
reach
"Curiously, the DUB3 gene, a part of the highly polymorphic RS447 megasatellite sequence, is induced by cytokines interleukin (IL-) 4 and IL-6 in certain mammalian cells XREF_BIBR XREF_BIBR."
28067227