IndraLab

Statements


IL6 activates USP17L2. 5 / 5
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"Interestingly, Dub3 activity and expression, at both the mRNA and protein levels, can be induced by IL-6 through the JAK and STAT3 signaling pathway [XREF_BIBR, XREF_BIBR, XREF_BIBR]."

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"In addition, the DUB-3 protein, induced by IL-4 and IL-6, is also involved in the regulation of cell growth and survival where its constitutive expression leads to growth suppression and apoptosis [25[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In addition, Dub3 can be rapidly induced by inflammatory cytokine IL-6 [XREF_BIBR, XREF_BIBR]."

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"Specifically, Dub3 is rapidly induced by IL-4 and IL-6."

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"Curiously, the DUB3 gene, a part of the highly polymorphic RS447 megasatellite sequence, is induced by cytokines interleukin (IL-) 4 and IL-6 in certain mammalian cells XREF_BIBR XREF_BIBR."