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USP47 deubiquitinates POLB. 2 / 3

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"USP47 may also be an oncology target, since it deubiquitinates DNA polymerase β (POLB) to regulate DNA base excision repair (BER) (Parsons et al. 2011)."

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"Specifically, USP47 deubiquitinates and stabilizes MAPK 25, DNA polymerase beta (Polbeta) 26, E-cadherin 27, beta-catenin 28, SNAIL 29, YAP 30, beta-Trcp 31, and katanin-p60 32."

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USP47 deubiquitinates POLB. 2 / 3

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