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RAD51 binds UCHL3. 23 / 23
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biogrid
No evidence text available
27941124
sparser
"Furthermore, wild-type RAD51 and the 3KR mutant bound equally with UCHL3, suggesting that RAD51 deubiquitination does not affect RAD51/UCHL3 interaction ()."
27941124
biogrid
No evidence text available
27941124
biogrid
No evidence text available
27941124
biogrid
No evidence text available
27941124
sparser
"We found that S75A mutation did not affect the interaction between UCHL3 and RAD51 ( xref G)."
27941124
sparser
"UCHL3 interacts with RAD51 and de-ubiquitinates residues that disrupt the RAD51–BRCA2 interaction."
31769469
sparser
"We also performed co-IP experiments to examine the changes in the interaction between RAD51 and UCHL3 in HEK293 cells that were treated with farrerol, and we excluded the possibility that farrerol promoted the deubiquitination of RAD51 by enhancing the UCHL3-RAD51 interaction (Supplementary Fig.  xref )."
37012254
sparser
"We performed in vitro and in vivo deubiquitination assay to establish that farrerol directly stimulates UCHL3 enzyme activity and promotes HR by UCHL3-RAD51 axis."
37012254
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"Here we carried out a systematic screen of DUBs for HR and established that UCHL3 interacts with and deubiquitinates RAD51 and promotes binding between RAD51 and BRCA2."
27941124
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"UCHL3 interacts with and deubiquitinates RAD51."
27941124
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"These results suggest a specific interaction between UCHL3 and RAD51 in cells."
27941124
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"We also performed co-IP experiments to examine the changes in the interaction between RAD51 and UCHL3 in HEK293 cells that were treated with farrerol, and we excluded the possibility that farrerol promoted the deubiquitination of RAD51 by enhancing the UCHL3-RAD51 interaction (Supplementary Fig. 3b, c)."
37012254
reach
"Furthermore, wild-type RAD51 and the 3KR mutant bound equally with UCHL3, suggesting that RAD51 deubiquitination does not affect RAD51/UCHL3 interaction (Supplemental Fig. S7B)."
27941124
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"Furthermore, the 3KR mutant enhanced the RAD51/BRCA2 interaction in UCHL3-deficient cells (Supplemental Fig. S7C)."
27941124
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"We found that S75A mutation did not affect the interaction between UCHL3 and RAD51 (Fig. 5G)."
27941124
sparser
"To test our hypothesis, we first examined whether UCHL3 interacts with RAD51."
27941124
sparser
"In addition, UCHL3 interacted with RAD51 when it formed a nucleoprotein filament with ssDNA ()."
27941124
sparser
"These results suggest a specific interaction between UCHL3 and RAD51 in cells."
27941124
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"Consist with this notion, it is suggested that UCHL3 interacts and deubiquitylates RAD51, which is required for the efficient HR [104]."
28764946
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"To determine whether the UCHL3–RAD51 interaction is direct, we generated and purified recombinant UCHL3 and RAD51."
27941124
sparser
"Purified His-RAD51 was able to interact with GST-UCHL3 under cell-free conditions even with a relatively high salt concentration in the washing buffer ( xref C), suggesting a direct interaction between UCHL3 and RAD51."
27941124
biogrid
No evidence text available
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