IndraLab

Statements

USP24 activates E2F4. 3 / 3
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"Further experiments reveal that USP24 knockdown decreases the stability of E2F4 protein, p130, and TFDP1, resulting in an increase in E2F1 levels and a promotion of the G1-S transition, ultimately lea[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Taken together, our results demonstrated that USP24 knockdown decreased E2F4, p130 and TFDP1, resulting in an increase in the E2F1 levels and a subsequent increase in the G1-S transition, leading to tumorigenesis."
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"However, we found that the ULK and LC3 gene expression was regulated by USP24-mediated E2F4 and E2F1 in interphase, and beclin-1 levels were increased by a decrease in TRAF6 levels in mitosis."
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