IndraLab

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LEF1 increases the amount of CYLD. 2 / 2

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"Chromatin immunoprecipitation assays revealed that lymphoid enhancer factor-1 (LEF1) dissociated from the CYLD promoter upon selenite treatment, thus abolishing suppression of CYLD gene expression."

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"This phenomenon is due to the downregulation of CYLD expression caused by the upregulation of LEF-1, which might be one reason of CLL pathogenesis and drug resistance."

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IndraLab

Statements

LEF1 increases the amount of CYLD. 2 / 2

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