IndraLab

Statements

ATXN3L decreases the amount of KLF5. 3 / 3
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"Knockdown of ATXN3L decreased KLF5 protein levels and inhibited the proliferation of breast cancer cells [XREF_BIBR]."
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"Nevertheless, ATXN3L increased the KLF5 protein stability and inhibited the expression of KLF5 downstream target genes, such as p21 and p27, and promote basal type breast cancer cell proliferation."
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"ATXN3L was identified as a candidate KLF5 DUB because the siRNA pool, and 2 out of 3 individual siRNA, against ATXN3L dramatically decreased the KLF5 protein level in HeLa."
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