IndraLab

Statements


EZH2 methylates SMAD3. 3 / 3
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sparser
"Smad3 methylation by EZH2 promotes its activation and tumor metastasis."

reach
"Smad3 methylation by EZH2 promotes its activation and tumor metastasis."

sparser
"Mechanistically, EZH2-triggered SMAD3 methylation facilitates SMAD3 interaction with its cellular membrane localization molecule (SARA), which in turn sustains SMAD3 phosphorylation by the TGFB receptor."