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KRAS increases the amount of USP28. 1 / 1
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"However, in contrast to the results in KRAS positive CRC cell lines, in WI-38 cells KRAS failed to increase ZNF304 protein levels (XREF_FIG) or significantly stimulate USP28 and PRKD1 transcription (XREF_FIG), explaining at least in part why KRAS expression does not result in INK4-ARF silencing."