IndraLab

Statements

USP2 inhibits Ubiquitin. 5 / 5
| 5
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"The inhibition of USP2 antagonizes ubiquitin-dependent degradation of cyclin D1 resulting in its stabilization."
32979815
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"USP2 directly interacts with cyclin D1 and promotes its stabilization by antagonizing ubiquitin dependent degradation."
19917254
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"Moreover, USP2 directly interacts with cyclin D1 and promotes its stabilization by antagonizing ubiquitin dependent degradation."
25972356
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"The ubiquitin dependent proteolysis of cyclin D1 is antagonized by the deubiquitinating enzyme USP2, thus increasing cyclin D1 half-life."
30853938
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"USP2 reverses ubiquitin‑mediated degradation of proteins and is involved in aberrant proliferation, migration, invasion, apoptosis and drug resistance of tumors."
37594087