IndraLab

Statements

USP15 binds TET2. 6 / 6
| 6
sparser
"Collectively, these data demonstrate that USP15 and TET2 physically interact with each other, and the CD domain of TET2 is responsible for their association."
| PMC
sparser
"USP15 binds to TET2."
| PMC
sparser
"To determine the functional significance of USP15-TET2 interaction, we first performed a dot blot experiment to determine 5hmC levels in cells ectopically expressing USP15."
| PMC
sparser
"Using antibodies that recognize TET2 or USP15, we detected endogenous interaction between USP15 and TET2 by reciprocal IP-Western assay in both human U2OS cells and mouse B16–ovalbumin (OVA) cells ( xref )."
| PMC
sparser
"First, USP15 directly interacts with TET2 ( xref ) and catalyzes the TET2 deubiquitylation."
| PMC
sparser
"To confirm the interaction of TET2 with USP15, we examined the binding of their association in cells when both proteins were ectopically expressed by IP–Western blot analysis."
| PMC