IndraLab

Statements


USP10 deubiquitinates His2Av. 3 / 3
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"USP10 specifically deubiquitylates H2A.Z and H2A."

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"In addition, the deubiquitination of H2A.Z by USP10 is required for the androgen-receptor mediated transcriptional activation of hormone regulated genes [XREF_BIBR]."

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"USP10 directly deubiquitylates H2A.Z in vitro and in vivo, and reducing USP10 expression in prostate cancer cells results in elevated steady-state levels of mono-ubiquitylated H2A.Z (H2A.Zub1)."