IndraLab

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USP24 deubiquitinates TP53. 7 / 7
1 | 6

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"These findings show that USP24 can deubiquitinate p53 in vitro."

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"They found also that USP24 deubiquitylates p53, activating the PUMA pathway, a regulator of DNA-damage-induced apoptosis."

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"Under both normal and stressed conditions p53 is also deubiquitinated by USP24 and thus stabilizing its level."

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"USP24 deubiquitinates p53 in vivo and in vitro."

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"Our data show that USP24 deubiquitinates p53 in vivo and in vitro, leading to p53 stabilization and activation."

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"In this study, we demonstrate that USP24 deubiquitinates p53 in human cells."