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USP13 activates ATP. 2 / 2

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"USP13 specifically deubiquitinates and thus upregulates ATP citrate lyase and oxoglutarate dehydrogenase, two key enzymes that determine mitochondrial respiration, glutaminolysis and fatty acid synthesis."

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"Therefore, USP13 suppression decreases ATP production by repressing the TCA cycle and inhibiting de novo lipogenesis [99]."

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USP13 activates ATP. 2 / 2

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