IndraLab

Statements

ERK phosphorylates KCND2 on S616. 5 / 5
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sparser
"ERK directly phosphorylates Kv4.2 at T602, T607, and S616 [ xref ]."
20600597
sparser
"Phosphorylation of Kv4.2 by ERK1/2 at residues T602, T607 and S616 has previously been shown in hippocampal neurons ( xref )."
26456351
sparser
"CamKII phosphorylates Kv4.2 at Ser438 while ERK phosphorylates Kv4.2 at T602, T607, and S616."
24404150
sparser
"It is noteworthy that ERK-mediated phosphorylation of Kv4.2 leads to decreased Kv4.2 and that ERK directly phosphorylates Kv4.2 at T602, T607, and Ser-616 ( xref )."
25541422
sparser
"Previous studies showed that Kv4.2 can be phosphorylated by extracellular signal-regulated kinases at Ser-616 resulting in suppression of the channel activity ( xref ), indicating that phosphorylation of Kv4.2 can lead to functional outcomes on K + currents."
25541422