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"For the VGCCs, it is reported that siRNA-mediated CACNA1G (Ca V 3.1) and CACNA1H (Ca V 3.2) downregulation suppresses cell proliferation, induces apoptosis, while AKT/mTORC2 axis activation sensitizes[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In human glioblastoma cells, mibefradil, a T-type Ca 2+ channel blocker with a weak L-type channel inhibiting activity [XREF_BIBR], and siRNA mediated downregulation of CACNA1G (Ca V.3.1) and CACNA1H (Ca V 3.2) reduces cell proliferation, induces apoptotic cell death, and sensitizes cells to ionizing radiation via AKT and mTORC2 axis [XREF_BIBR]."
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