IndraLab

Statements


USP22 decreases the amount of Cyclin. 5 / 5
| 5

reach
"Mechanistically, we found that USP22 depletion dramatically decreased Akt phosphorylation and cyclin D2 expression."

reach
"Furthermore, USP22 small interfering (si)RNA decreased the expression of Cyclin B and Survivin, and increased the expression of p21 in HCC (7)."

reach
"USP22 siRNA also increased the expression of p21 and reduced the expression of Cyclin B in OSCC cells."

reach
"Furthermore, USP22 small interfering RNA inhibited cell growth and reduced the expression levels of Aurora-B, Survivin and Cyclin B, together with the upregulation of cyclin-dependent kinase inhibitor 1A (p21)."

reach
"Moreover, USP22 siRNA increased the p21 protein levels and decreased the Cyclin B protein levels in OSCC cells (Fig. 2A)."