IndraLab

Statements

YOD1 inhibits coagulation. 5 / 5
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"YOD1 suppressed coagulation primarily via inhibiting NLRP3 inflammasome activation."
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"We hypothesized that YOD1 suppressed coagulation primarily via inhibiting NLRP3 inflammasome activation."
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"Taken together, we confirmed that YOD1 suppressed coagulation primarily via inhibiting NLRP3 inflammasome activation."
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"Deficiency of YOD1 expression enhanced NLRP3 inflammasome activation and coagulation both in vitro and in vivo."
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"Mechanically, upon methicillin-resistant Staphylococcus aureus (MRSA) infection in macrophages, YOD1 interacted with NLRP3 to specifically remove its K33-linked ubiquitination, subsequently inhibiting NLRP3 inflammasome activation and coagulation."
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