IndraLab

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"Potentiation of BK channel activity by the mu selective agonist [D-Ala2, N-Me-Phe4, Gly5-ol]-enkephalin (10 nM) was unaffected by all attempts to disrupt or alter G protein function, including incubation of cells with pertussis toxin (PTX) and inclusion of guanosine 5 '-O-(2-thio) diphosphate (GDP beta S) or guanosine 5 '-O-(3-thio) triphosphate (GTP gamma S) in intracellular recording solutions."