IndraLab

Statements

Azithromycin inhibits KCNH2. 4 / 4
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"Significance Statement This work demonstrates that among off-label potential COVID-19 treatment drugs chloroquine, hydroxychloroquine, azithromycin, and remdesivir, the former two drugs block hERG potassium channels while the latter two drugs do not."
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"(1) Azithromycin reduced hERG currents by accelerated channel inactivation."
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"Azithromycin weakly blocks hERG from conducting potassium ions across the cardiac membrane while chloroquine and hydroxychloroquine decrease the number of ions available for transit."
| PMC
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"Azithromycin weakly blocks hERG from conducting potassium ions across the cardiac membrane while chloroquine and hydroxychloroquine decrease the number of ions available for transit ."
| PMC