IndraLab

Statements

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"Additionally, the combination of palmitate and LPS also reduced IkBalpha at 60 min and IkBbeta in cytoplasm at 10 min."
30273577
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"Subsequently, we observed that oleate was able to partially prevent IkappaB-alpha degradation induced by TNF-alpha or palmitate."
26055507
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"It also has been shown to prevent palmitate induced IkappaBalpha degradation, RelA nuclear translocation, NO production, and cytokine secretion [XREF_BIBR], Besifloxacin is a novel fluoroquinolone initially developed by Bausch & Lomb for the topical treatment of ophthalmic infections [XREF_BIBR]."
29707159
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"PA stimulation promotes macrophage I kappa B alpha (IkappaBalpha) degradation, janus kinase (JNK) phosphorylation, with TNF-alpha and IL-6 secretion in vitro."
27128935
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"C16 significantly decreased levels of phospho-IKKalpha / beta ( Figure 3A , 3B ) , phospho-p65 ( pp65 ) ( Figure 3A , 3C ) and phospho-IkappaBalpha , Figure 3A , 3D ) , and suppressed degradation of IkappaBalpha ( Figure 3A , 3E ) after LPS stimulation ."
33017381
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"PO also prevented PA induced IkappaBalpha degradation, RelA nuclear translocation, NO production, and cytokine secretion."
25987561
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"The co-treatment with 400muM linoleate inhibited phospho-c-Jun N-terminal kinase (pJNK) activation and IkBalpha reduction caused by 500muM palmitate treatment."
24885871
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"We found that SP rapidly reduces IkappaB-alpha protein level in the cytosol while pre-treatment with OLE restores normal cytoplasmatic IkappaB-alpha level in RAW264.7 macrophages, suggesting that OLE inhibited SP induced IkappaB-alpha degradation and, thus, NF-kappaB activation (XREF_FIG I)."
33260769
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"Myoblasts treated with palmitate exhibit activation of pathways leading to inflammation, specifically activating MAPK, elevating ROS and inducing IkappaBalpha degradation."
23078640
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"In NRK-52E cells treated with PA for 30 min, EGFR silencing inhibited PA induced IkappaBalpha degradation and protein expression of cell adhesion molecules VCAM-1 and ICAM-1."
27014908