IndraLab

Statements

EGF leads to the phosphorylation of GRB2 on Y209. 2 / 2
2 |
bel
"We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database"
17081983
bel
"For example, debate has raged for years as to whether Grb2, a key adaptor protein, undergoes tyrosine phosphorylation (Li et al., 2001). Here we identified two phosphorylation sites on Grb2 with certainty: Tyr169 and Tyr209, both located within the carboxy-terminal SH3 domain (see Table S2). (Taken from Discussion section)"
17081983