IndraLab
Statements
Hydroxychloroquine inhibits EDN1. 4 / 4
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4
reach
"HCQ has been shown to improve endothelialOcular Immunology & Inflammation Choroidal Thickness Changes in Rheumatoid Arthritis 5function in mice models.23 Moreover, treatment with HCQ is associated with a decline in serum ET-1 levels.23,24 24 Rahman et al. 25 reported that HCQ significantly reduced the production of TNF-alpha and ET-1."
reach
"A study of the extension of the endothelial protective effect on PE that used an in vitro model of tumor necrosis factor-α and PE serum-induced dysfunction suggested that HCQ significantly attenuated the production of tumor necrosis factor-α and PE serum-induced endothelin-1 [44]."