
IndraLab
Statements
reach
"To model gene dose insufficiency by RNA interference (RNAi), we used a set of eight shRNA expression vectors in the MDS and AML cell line SKM1, which reduced MYBL2 expression to 5-30% of the endogenous MYBL2 levels (XREF_FIG), approximating the endogenous levels we had identified in CD34+ cells from patients (XREF_FIG)."