IndraLab

Statements

USP8 activates sub. 1 / 1

| 1

reach

"The putative substrate of BRUCE could be USP8 and if this is the case, ubiquitination of USP8 by BRUCE is expected to enhance its Dub activity over Ub-BRIT1, thereby facilitating removal of the Ub chains from K63-Ub-BRIT1 and promoting recruitment of de-ubiquitinated BRIT1 to sites of DNA damage."

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INDRA sources:

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IndraLab

Statements

USP8 activates sub. 1 / 1

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