IndraLab

Statements

USP8 activates sub. 2 / 2
| 2
reach
"These data suggest that USP8 phosphorylation, possibly on Tyr residue (s), enhances its DUB activity."
29472535
reach
"The putative substrate of BRUCE could be USP8 and if this is the case, ubiquitination of USP8 by BRUCE is expected to enhance its Dub activity over Ub-BRIT1, thereby facilitating removal of the Ub chains from K63-Ub-BRIT1 and promoting recruitment of de-ubiquitinated BRIT1 to sites of DNA damage."
26683461