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USP39 activates phosphatidylinositol 3-kinase/protein kinase B signal transduction. 2 / 2

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"Cai et al. [52] reported that USP39 promotes PC cell apoptosis by regulating the AKT signaling pathway."

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"Xu et al. reported that the knockdown of USP39 increased the levels of apoptosis-related proteins, such as caspase-3, caspase-8, caspase-9, and PARP, in RCCs, and inhibited the activation of ERK and AKT signaling pathways, resulting in an increase in the apoptosis rate of cancer cells [55]."

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USP39 activates phosphatidylinositol 3-kinase/protein kinase B signal transduction. 2 / 2

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