IndraLab

Statements

Resveratrol inhibits TICAM1. 7 / 7
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"Resveratrol inhibits the TRIF dependent pathway by upregulating sterile alpha and armadillo motif protein, contributing to anti-inflammatory effects after respiratory syncytial virus infection."
24478430
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"Together, these results demonstrate that resveratrol specifically inhibits TRIF signaling in the TLR3 and TLR4 pathway by targeting TANK binding kinase 1 and RIP1 in TRIF complex."
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"Resveratrol specifically inhibits TRIF signaling in the TLR3 pathway by targeting TBK1 and RIP1 in TRIF complex, resulting in inhibition of pro inflammatory cytokines expression [XREF_BIBR]."
29050325
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"28 Resveratrol, an antioxidant found in red wine, inhibits TRIF dependent activation, 29 and, like GA, reduces clinical EAE and macrophage mediated inflammatory activity."
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"Furthermore, the suppressive effect of resveratrol on LPS induced NF-kappaB activation was abolished in TRIF deficient mouse embryonic fibroblasts, but not in MyD88 deficient macrophages (XREF_FIG), suggesting that resveratrol specifically inhibits MyD88 independent signaling pathways downstream of TLR3 and TLR4."
21631512
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"We hypothesize that resveratrol inhibits the TRIF dependent pathway through upregulation of SARM post-RSV infection."
24478430
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"The suppressive effect of resveratrol on LPS induced NF-kappaB activation was abolished in TRIF deficient mouse embryonic fibroblasts, whereas LPS induced degradation of IkappaBalpha and expression of cyclooxygenase-2 and inducible NO synthase were still inhibited in MyD88 deficient macrophages."
16116226