IndraLab

Statements



reach
"As shown in Fig. 5i, j, USP13 overexpression significantly suppressed IκBα degradation while USP13 downregulation accelerated IκBα degradation.USP13 is a deubiquitinase (DUB) and regulates IκBα stability, therefore, analyses were performed to explore if USP13 regulates IκBα ubiquitination."

reach
"As shown in Fig. 5i, j, USP13 overexpression significantly suppressed IκBα degradation while USP13 downregulation accelerated IκBα degradation.USP13 is a deubiquitinase (DUB) and regulates IκBα stability, therefore, analyses were performed to explore if USP13 regulates IκBα ubiquitination."

reach
"Thr122 phosphorylation could affect the ubiquitination status of USP13 by inhibiting the binding of E3 ubiquitin ligase or promoting the binding of deubiquitinase on USP13."