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COPS6 deubiquitinates FOS. 3 / 3
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"Since CSN6 has the activity of deubiquitinase, so we next asked whether CSN6 deubiquitinates c-Fos."

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"We analyzed c-Fos ubiquitination in the presence of MG132 and found that MG132-induced c-Fos ubiquitination was abolished by overexpression of CSN6, on the contrary, knocking down of CSN6 increase the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In summary, Our results demonstrated that CSN6 inhibited ubiquitination of c-Fos via its deubiquitination function, thus stabilized c-Fos protein.The main causes of cancer-related death are metastasis[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"