IndraLab

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"It has been confirmed that USP20 can cause D2, HIF-1α, β2-AR, TRAF6, Tax and PKM2 to deubiquitinate, thereby regulating thyroid hormone activation, cell cycle regulation, inflammatory response, tumori[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Previous publications have identified β-catenin as an oncogene [62], prompting us to speculate that USP20 promotes tumorigenesis by regulating β-catenin stability."

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"USP20 promotes the tumorigenesis of several cancer types, such as breast and cervical cancer; however, it exhibits inhibitory effects on GC [16]."