IndraLab

Statements



reach
"A subsequent study showed that both CSPα and HSC70 functioned downstream of USP19 to promote MAPS as knockdown of CSPα or HSC70 inhibited USP19-induced protein secretion (Xu et al., 2018)."

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"This likely represents a small fraction of physiological MAPS cargoes because the experiments were conducted under serum-depleted culture condition, which, while being necessary to eliminate serum contaminants from the secretome and allow mass spectrometry, is known to diminish USP19-mediated unconventional protein secretion (21)."

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"Both CSPα and HSC70 function downstream of USP19 because the downregulation of CSPα or HSC70 inhibits USP19-induced protein secretion (Xu et al., 2018)."