IndraLab

Statements

STAMBPL1 increases the amount of GRHL3. 8 / 8
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"Furthermore, we discovered that STAMBPL1 regulates GRHL3 transcription by interacting with the transcription factor FOXO1."
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"Silencing of STAMBPL1 inhibited GRHL3 transcription in both HCC1806 and HCC1937 cells (Figure 4B, Figure 4—figure supplement 1B)."
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"Conversely, the overexpression of STAMBPL1 promoted GRHL3 transcription (Figure 4D, Figure 4—figure supplement 1D)."
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"STAMBPL1 mediates GRHL3 transcription by interacting with FOXO1."
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"Therefore, we aimed to investigate whether STAMBPL1 promotes GRHL3 transcription via FOXO1."
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"To investigate the mechanism by which STAMBPL1 promotes GRHL3 transcription through FOXO1, we conducted immunofluorescence and immunoprecipitation assays."
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"These findings suggest that STAMBPL1 promotes GRHL3 transcription by interacting with FOXO1."
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"Through RNA-seq analysis, we revealed that STAMBPL1 positively regulates the transcription of GRHL3."
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