IndraLab

Statements

GPCR activates KCNK2. 3 / 3
| 2 1
sparser
"Previous studies have indicated that both Trek1 and Trek2 can be activated by GPCRs linked to G i/o G proteins (Fink et al., xref ; Patel et al., xref ; Lesage et al., xref ; Murbartian et al., xref ; Deng et al., xref ; Xiao et al., xref ), and both channels are expressed in the mouse midbrain (Lein et al., xref )."
22973213
reach
"GPCRs are also able to both positively and negatively modulating KCNK2 activity, a process reliant on the phosphorylation of critical serine residues by either PKA or PKC ."
30333618
reach
"Previous studies have indicated that both Trek1 and Trek2 can be activated by GPCRs linked to G G proteins (Fink et al., 1996; Patel et al., 1998; Lesage et al., 2000; Murbartian et al., 2005; Deng et al., 2009; Xiao et al., 2009), and both channels are expressed in the mouse midbrain (Lein et al., 2007)."
22973213