IndraLab

Statements


GPCR activates KCNK2. 4 / 4
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reach
"GPCRs are also able to both positively and negatively modulating KCNK2 activity, a process reliant on the phosphorylation of critical serine residues by either PKA or PKC ."

reach
"Further studies indicate that several other G i/o -coupled GPCRs, including GABA B Rs, A 1 Rs, and CB 1 Rs, stimulate fast astrocytic glutamate release, opening the glutamate-permeable, two-pore domai[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"Previous studies have indicated that both Trek1 and Trek2 can be activated by GPCRs linked to G i/o G proteins (Fink et al., xref ; Patel et al., xref ; Lesage et al., xref ; Murbartian et al., xref ; Deng et al., xref ; Xiao et al., xref ), and both channels are expressed in the mouse midbrain (Lein et al., xref )."

reach
"Previous studies have indicated that both Trek1 and Trek2 can be activated by GPCRs linked to G G proteins (Fink et al., 1996; Patel et al., 1998; Lesage et al., 2000; Murbartian et al., 2005; Deng et al., 2009; Xiao et al., 2009), and both channels are expressed in the mouse midbrain (Lein et al., 2007)."