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COPS6 inhibits Hypertrophy. 3 / 3
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"What's more, we knocked down Nkx2.2 in CSN6-overexpressing NRCMs, and found that the downregulation of Nkx2.2 rescued the decrease of SIRT2's expression and cardiomyocyte hypertrophy caused by overexp[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Down-regulation of CSN6 could attenuate Ang II-induced cardiomyocyte hypertrophy based on the results that the size of cardiomyocyte and the expression levels of fetal genes were decreased in CSN6-sil[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Further, we upregulated Nkx2.2 in CSN6-silencing NRCMs, and found that overexpression of Nkx2.2 attenuated the increase of SIRT2's expression and cardiomyocyte hypertrophy induced by CSN6 inhibition ([MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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