IndraLab

Statements

USP14 decreases the amount of MDM2. 3 / 3
| 3
reach
"USP14 inhibition downregulates AR and PSA and increases MDM2 expression."
28151478
reach
"Our current study showed that IU1, a pharmacological deubiquitinating enzyme USP14 selective inhibitor, dramatically decreased MDM2 level, blocked G0/G1 to S phase transition, decreased cell growth and triggered cell apoptosis in cervical cancer cells, suggesting that targeting USP14 and MDM2 axis could be a potential strategy for cervical cancer therapy."
33061808
reach
"As shown above, USP14 decreases the expression and phosphorylation of MDM2."
28151478