IndraLab

Statements


BAP1 activates RCC. 2 / 2
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"Multiple lines of evidence implicate HCF-1 in BAP1 mediated RCC tumor suppression function."

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"Here, we report a novel RCC GEMM based on Pax8-Cre deletion of Vhl together with either Bap1 or Pbrm1, and show that Bap1 and Pbrm1 are not only drivers of RCC, but also determinants of tumor grade."