IndraLab

Statements


Ube4b activates ATXN3. 1 / 1
| 1

reach
"We found that E4B targets the pathological form of ataxin-3 -- in which abnormal expansion of a polyglutamine tract is responsible for spinocerebellar ataxia type 3 (SCA3) in humans -- for ubiquitylation and degradation in mammalian cells as well as in a Drosophila melanogaster model of SCA3 [XREF_BIBR]."