IndraLab

Statements


OTUB1 inhibits AKT. 2 / 2
| 2

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"In addition, Otub1 deletion in cells enhanced AKT activity, leading to a larger cell size, higher ATP levels and reduced AMPK phosphorylation."

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"The PI3K and AKT pathway integrates the TCR and CD28 and IL-15R signals and is negatively regulated by the DUB Otub1."