IndraLab

Statements

OTUB1 inhibits AKT. 2 / 2

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"In addition, Otub1 deletion in cells enhanced AKT activity, leading to a larger cell size, higher ATP levels and reduced AMPK phosphorylation."

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"The PI3K and AKT pathway integrates the TCR and CD28 and IL-15R signals and is negatively regulated by the DUB Otub1."

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INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

OTUB1 inhibits AKT. 2 / 2

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