IndraLab

Statements

USP8 is phosphorylated on S716. 7 / 7
4 | 3
sparser
"This stabilization is phosphorylation‐dependent, as USP8 phosphorylation at Ser716 facilitates its interaction with OGT."
40537889
hprd
No evidence text available
20068231
sparser
"In hepatocellular carcinoma, the STE20-like kinase (SLK) mediates the phosphorylation of the S716 site of USP8, significantly enhancing its binding ability to OGT; interestingly, the catalytic subunit alpha of protein phosphatase 1 (PPP1CA) can reverse this binding effect through dephosphorylation [ xref ]."
41331709
hprd
No evidence text available
20166139
hprd
No evidence text available
19651622
hprd
No evidence text available
18452278
sparser
"Mechanistical studies reveal that USP8 stabilizes O-GlcNAc transferase (OGT) via inhibiting K48-specific poly-ubiquitination process on OGT protein at K117 site, and STE20-like kinase (SLK)-mediated S716 phosphorylation of USP8 is required for the interaction with OGT."
37867237