IndraLab

Statements


USP25 activates GLI1. 4 / 4
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"Altogether, these data indicate that USP21 regulates the Hh signaling pathway, and either directly or indirectly modulates Gli1 transcriptional activity."

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"USP21 promotes Gli1 localisation at the centrosome."

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"USP21 binds to and stabilizes Gli1, and knockdown of USP21 decreases the transcriptional activity of Gli1 (Figure 3)."

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"USP21 regulates the Hh signaling pathway and modulates Gli1 transcriptional activity."