IndraLab

Statements

KCNQ1 activates KCN. 3 / 3
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"E2 (100 nM) reduced the currents mediated by the KCNQ1 : KCNE3 potassium channel and had no effect on currents via KCNQ1 : KCNE1 or KCNQ1 alone."
21911611
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"XREF_BIBR, XREF_BIBR Rare mutations in KCNQ1 are known to cause potassium channel dysfunction leading to a form of cardiac long QT syndrome (LQT1) and serious arrhythmias, ventricular fibrillation and cardiac arrest."
22151254
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"1 It is caused by mutations in the KCNQ1 gene that impair the slow acting potassium channel that gives rise to I Ks."
22293141