IndraLab

Statements



reach
"XREF_BIBR P6 suppressed the IFN-gamma and STAT1, IL-2 and STAT5, and IL-4 and STAT6 signaling pathways strongly while it suppressed IL-6 and STAT3 pathway only modestly, resulting in reduction of the Th1 and Th2 responses but the enhancement of the T17 response."

reach
"While p-STAT1 was considerably increased in both cell lines in the presence of cisplatin, P6 almost entirely suppressed p-STAT1 in both cell lines."

reach
"We also demonstrated that BMDMs from STAT1 -/- mice and BMDMs from WT mice treated with JAK-I inhibitor failed to induce the expression of Dll1 following stimulation with PolyI : C, H1N1 or rIFN-beta (XREF_FIG E and F)."