
IndraLab
Statements
OTUB1 inhibits necroptotic process. 6 / 6
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2
4
reach
"Combined in vivo and in vitro experiments comprising mice lacking OTUB1 specifically in liver parenchymal cells (OTUB1 LPC-KO) and human OTUB1 deficient HepG2 cells revealed that OTUB1 prevented hepatocyte necroptosis but not apoptosis upon infection with Lm and DGal and TNF challenge."