IndraLab

Statements


CYLD inhibits NFKBIA. 2 / 2
| 2

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"Treatment with BAY 11-7085, a known NF-kappaB antagonist that blocks IkappaBalpha phosphorylation and NF-kappaB transactivation, effectively abrogated the CYLD siRNA induced IkappaBalpha degradation."

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"While the CYLD deficiency slightly decreased the basal expression levels of IkappaBalpha and IkappaBbeta proteins, it did not affect the basal expression of IkappaBepsilon in RASMCs (XREF_FIG)."