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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

Modified BAP1 decreases the amount of SLC7A11. 2 / 2

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"We confirmed that re-expression of BAP1 WT, but not its C91A mutant, in UMRC6 cells decreased SLC7A11 expression (XREF_FIG), suggesting that BAP1 mediated repression of SLC7A11 expression requires BAP1 's DUB activity."

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"Similarly, BAP1 re-expression in NCI-H226 cells, a BAP1 deficient mesothelioma cell line with high SLC7A11 expression (see XREF_FIG), also repressed SLC7A11 expression (XREF_SUPPLEMENTARY - XREF_SUPPLEMENTARY)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...