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Ala-Pro inhibits STING1. 1 / 1

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"Last, our data also show that the JB419 cell-permeant nonhydrolyzable analog of Ap 4 A antagonizes STING to levels similar to those observed for Ap 4 A. Thus, this compound bears the potential for translation to the clinic and opens the way to the design of derived compounds with higher affinity for STING or increased retention time in the cGAMP binding pocket."

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IndraLab

Statements

Ala-Pro inhibits STING1. 1 / 1

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