IndraLab

Statements

OTUD1 activates Interferon. 2 / 2

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"Both Smurf1 and the deubiquitinase activity of OTUD1 are required for OTUD1 mediated downregulation of MAVS/TRAF3/TRAF6 and inhibition of interferon antiviral response."

29734366

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reach

"OTUD1 negatively regulates the canonical NF-κB activation, apoptosis, and necroptosis, whereas OTUD1 upregulates the interferon (IFN) antiviral pathway."

35941131

INDRA sources:

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IndraLab

Statements

OTUD1 activates Interferon. 2 / 2

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