IndraLab

Statements

USP7 deubiquitinates PCNA. 6 / 6
1 | 5
reach
"Whereas Rad6/Rad18 E2 conjugate/E3 ligase cause PCNA monoubiquitination, Usp1 and Usp7 cause PCNA deubiquitination with some difference in case of HU (Niimi et al, 2008; Fox et al, 2011)."
34272328
reach
"Cell-cycle-synchronization analyses revealed that USP7 suppression increased H2O2 induced PCNA ubiquitination throughout interphase, whereas USP1 suppression specifically increased ubiquitination in S-phase cells."
26673319
reach
"USP7 can deubiquitinate PCNA alongside a related DUB, USP1."
35005106
ubibrowser
"Review"
28031783
reach
"Kashiwaba et al. have additionally shown that USP7 can deubiquitylate PCNA, but this is not coupled to DNA replication and likely plays a role in DNA repair."
29357069
reach
"Surprisingly, USP7 also deubiquitylates PCNA."
27242895